Effect of cardiopulmonary bypass on cytokine network and myocardial cytokine production
نویسندگان
چکیده
منابع مشابه
Effects of cardiopulmonary bypass on lung nuclear factor-kappa B activity, cytokine release, and pulmonary function in dogs
Objective(s): To study the effect of cardiopulmonary bypass (CPB) on nuclear factor-kappa B (NF-кB) and cytokine expression and pulmonary function in dogs. Materials and Methods: Twelve male mongrel dogs were divided into a methylprednisolone group (group M) and a control group (group C). All animals underwent aortic and right atrial catheterization under general anesthesia. Changes in pulmonar...
متن کاملCytokine responses to myocardial revascularization on cardiopulmonary bypass: intermittent crossclamping versus blood cardioplegic arrest.
BACKGROUND The inflammatory responses to the different myocardial protection approaches have not been thoroughly investigated. We sought to study the cytokine responses to cardiopulmonary bypass (CPB) using the intermittent aortic crossclamping with ventricular fibrillation (IAC) versus blood cardioplegic arrest (BC) techniques. METHODS Perioperative plasma levels of tumor necrosis factor a (...
متن کاملEvidence of systemic cytokine release in patients undergoing cardiopulmonary bypass.
Cardiopulmonary bypass (CPB) causes a systemic inflammatory response syndrome (SIRS), which can progress to an acute lung inflammation known as postperfusion syndrome. We developed a two-phase hypothesis: first, that SIRS, as indicated by elevated cytokines post-CPB, would be correlated with postoperative pulmonary dysfunction (Phase I), and second, that the cytokine interleukin-6 (IL-6) is pre...
متن کاملInhaled carbon monoxide attenuates myocardial inflammatory cytokine expression in a rat model of cardiopulmonary bypass.
Carbon monoxide (CO), a by-product of Heme metabolism, is a potent modulator of inflammation. Low dose inhaled CO has demonstrated reduced lung and kidney injury in animal models of cardiopulmonary bypass (CPB). We evaluated the impact of low dose inhaled CO on systemic, pulmonary, and myocardial inflammatory response to CPB in rats. Sixteen male Sprague-Dawley rats underwent CPB for 1 hour. Th...
متن کاملCytokine Production in Hymenolepis Nana Infection
Background: Although many experimental studies provide convincing evidence that type II immunity is protective against helminths, recent data in mice demonstrate that Th1 is also impor-tant in some cestodes like Hymenolepis nana. Objective: To identify the role of Th1 and Th2 lymphocytes in immunity against H. nana, the levels of IL-12, IFNγ, IL-5, and IL-13 were de-termined in serum of humans ...
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ژورنال
عنوان ژورنال: Clinical Cardiology
سال: 2006
ISSN: 0160-9289,1932-8737
DOI: 10.1002/clc.4960290708